It should be noted that in theory if one was to consistently suppress your natural estrogen levels for a long period of time, this would negatively impact your health, including your cholesterol. Due to the ability of Letrozole- to inhibit estrogen so much, this should definitely be a concern to most users. However the research that has focused on the relationship between use of letrozole and cholesterol levels is rather inconsistent in it's findings. Many studies have concluded that the compound is detrimental to both a user's HDL and LDL cholesterol levels, while other research has found no link. Obviously individuals are best served to monitor their cholesterol while using any compound via blood tests however barring that, letrozole should simply not be run for extended periods of time if at all possible. Doing so could cause serious medical complications.
Along with the issues related to blood lipids is the fact that many users complain that their libido is dramatically reduced when using the compound. This is related to the fact that estrogen is partly responsible for the regulation of an individual's sex drive. Since Letrozole- is so potent it can often drive estrogen levels too low and this inhibits a user's libido. To avoid this users can lower dosages, but some anecdotally report that even extremely low doses of the drug can cause problems. If this is the case a less potent compound such as exemestane or anastrozole may be a more appropriate option.
In August of 2009, I suffered a severe meniscus tear in my left knee, pain level out of 10. This occurred in my sleep while trying to untangle sheets that had wrapped around my ankles. I had awoken suddenly to severe pain that that only got worse as the injury began to swell under my kneecap. This injury rendered me unable to walk and getting out of bed took 5 - 10 minutes. I would prop myself up on crutches with a pillow in my mouth to bite down on and stifle my yelling as to not disturb the rest of my family, while I straightened my leg. I needed to do this every time before I could begin a trip to the bathroom; which at 49 years old is a 3am occurrence every night. I knew I was a candidate for arthroscopic surgery. I had major and minor surgies over the past two years and was not excited about another one. I started to research options online when I stumbled upon The MendMeShop. After reading the testimonies and weighing the cost, I decided to give the Knee Inferno and Knee Freezie a try! BOY! AM I GLAD THAT I DID!! Within a couple of weeks, I was able to get rid of the crutches and was 95% pain free in 8 weeks, completely healed and back on a treadmill two weeks after that. I have a friend at church who had the same injury, opted for surgery, and took 12 weeks to heal. Purchasing the wraps was by far the wisest medical treatment decision I have ever made for two reasons. Once you have surgery you are never the same,(with knee surgery you are almost guaranteed arthritis in the affected area within ten years or less), and the healing process was quicker without having to undergo invasive surgery. Thank you MendMeShop!! Fan For Life
Before your surgeon uses one of these techniques to fix your meniscus tear, they will perform additional work called debridement and abrasion to prepare your tissue for the repair. Debridement of your meniscus tear is done in order to remove dead, hardened, or contaminated tissue. If you have an open wound the removal of any foreign substances found in the knee will be done. Your surgeon will then scrape down and smooth out (abrade) your tissue to make it easier for the edges of your tear to come together. Abrasion can also trigger bleeding of your meniscal tissue. Bleeding in your meniscus is something that your surgeon wants to happen because it will stimulate healing of your meniscus after the surgery.